Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | Q9HBH1 | 1/20 | 0.35 | |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.35 |
| ▸ | GSK3B | P49841 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984850 | 0.83 | HDAC6 (0.40) | LRRK2DYRK1AGSK3BGAAPOLB | |
| SCHEMBL19981145 | 0.83 | BMP1 (0.49) | BMP1DPP4DPP8DPP9DPP7 | |
| SCHEMBL19981328 | 0.83 | BMP1 (0.36) | BMP1DPP4DPP8DPP9DPP7 | |
| SCHEMBL19981308 | 0.77 | BMP1 (0.39) | BMP1DPP4DPP8DPP9DPP7 | |
| SCHEMBL19981246 | 0.76 | BMP1 (0.40) | BMP1DPP4DPP8DPP9DPP7 | |
| SCHEMBL19981329 | 0.75 | VSIR (0.44) | BMP1DPP4DPP8DPP9DPP7 | |
| SCHEMBL19981138 | 0.74 | BMP1 (0.49) | BMP1DPP4DPP8DPP9DPP7 | |
| SCHEMBL18078059 | 0.73 | BMP1 (0.46) | BMP1DPP4DPP8DPP9DPP7 | |
| SCHEMBL19981171 | 0.72 | BMP1 (0.41) | BMP1DPP4DPP8DPP9DPP7 | |
| SCHEMBL19981330 | 0.70 | BMP1 (0.40) | BMP1DPP4DPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018051254-A1 | CYCLIC SUBSTITUTED-1,2,4-OXADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-03-22 | — | — | WO | disclosed |