Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | KCNT1 | Q5JUK3 | 5/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | Q9HBH1 | 1/20 | 0.33 | |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KLK3 | P07288 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | VSIR | Q9H7M9 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19973940 | 0.84 | MAPK1 (0.33) | MAPK1SYK | |
| SCHEMBL19973939 | 0.84 | MAPK1 (0.33) | MAPK1SYK | |
| SCHEMBL19981161 | 0.77 | POLB (0.42) | BMP1L3MBTL1MAPK1KLK3 | |
| SCHEMBL19981277 | 0.75 | TDP1 (0.45) | L3MBTL1TDP1ATMNPC1PKM | |
| SCHEMBL19981330 | 0.73 | BMP1 (0.40) | BMP1DPP4DPP8DPP9DPP7 | |
| SCHEMBL19867019 | 0.72 | CD274 (0.61) | BMP1DPP4DPP8DPP9DPP7 | |
| SCHEMBL18077966 | 0.72 | CD274 (0.61) | BMP1DPP4DPP8DPP9DPP7 | |
| SCHEMBL18078059 | 0.71 | BMP1 (0.46) | BMP1DPP4DPP8DPP9DPP7 | |
| SCHEMBL19981171 | 0.71 | BMP1 (0.41) | BMP1DPP4DPP8DPP9DPP7 | |
| SCHEMBL19981329 | 0.70 | VSIR (0.44) | BMP1DPP4DPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018051254-A1 | CYCLIC SUBSTITUTED-1,2,4-OXADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-03-22 | — | — | WO | disclosed |