Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19973940 | 1.00 | MAPK1 (0.33) | MAPK1MEN1POLBKMT2AKDM4E | |
| SCHEMBL19981276 | 0.84 | BMP1 (0.38) | MAPK1SYK | |
| SCHEMBL19984852 | 0.74 | KDM4E (0.37) | MEN1KMT2AKDM4ENLRP3 | |
| SCHEMBL19984831 | 0.72 | LRRK2 (0.35) | MEN1POLBKMT2A | |
| SCHEMBL18078725 | 0.72 | CD274 (0.52) | MEN1POLBKMT2AKDM4E | |
| SCHEMBL19866357 | 0.72 | CD274 (0.52) | MEN1POLBKMT2AKDM4E | |
| SCHEMBL19984824 | 0.70 | HDAC6 (0.34) | KDM4E | |
| SCHEMBL19984850 | 0.69 | HDAC6 (0.40) | POLB | |
| SCHEMBL19984975 | 0.66 | TRHR (0.36) | — | |
| SCHEMBL26671383 | 0.62 | KDM4E (0.47) | MEN1KMT2AKDM4ENLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018051255-A1 | CYCLIC SUBSTITUTED-1,3,4-OXADIAZOLE AND THIADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-03-22 | — | — | WO | disclosed |
| WO-2018051255-A1 | CYCLIC SUBSTITUTED-1,3,4-OXADIAZOLE AND THIADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-03-22 | — | — | WO | disclosed |