Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10160074 | 0.78 | RORC (0.33) | — | |
| SCHEMBL22349071 | 0.73 | ALDH1A1 (0.33) | DRD2 | |
| SCHEMBL9944465 | 0.71 | KCNH2 (0.38) | — | |
| SCHEMBL12712697 | 0.71 | CNR2 (0.37) | DRD2HTR2AHTR2C | |
| SCHEMBL9924111 | 0.70 | NOS3 (0.31) | — | |
| SCHEMBL9911490 | 0.70 | SLC6A4 (0.31) | — | |
| SCHEMBL9924119 | 0.70 | KCNQ3 (0.30) | — | |
| SCHEMBL24914244 | 0.68 | HRH3 (0.35) | — | |
| SCHEMBL12872465 | 0.68 | HRH3 (0.33) | HTR2AHTR2C | |
| SCHEMBL13600627 | 0.68 | HRH3 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2365970-B1 | PYRIDAZINONES AND THEIR USE AS BTK INHIBITORS | GILEAD CONNECTICUT INC (US) | 2018-03-21 | — | — | EP | disclosed |