Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21154235 | 0.78 | LPL (0.49) | LPLLIPG | |
| SCHEMBL8081012 | 0.78 | LPL (0.31) | LPLLIPG | |
| SCHEMBL1290153 | 0.77 | LPL (0.51) | LPLLIPG | |
| SCHEMBL23153800 | 0.77 | — | — | |
| SCHEMBL25902940 | 0.76 | CYP3A4 (0.34) | LPLLIPG | |
| SCHEMBL14700056 | 0.76 | — | — | |
| SCHEMBL23635134 | 0.75 | PDGFRB (0.34) | — | |
| SCHEMBL26834607 | 0.73 | MAPT (0.32) | — | |
| SCHEMBL1130911 | 0.73 | HSPB1 (0.34) | LPLLIPG | |
| SCHEMBL19003095 | 0.72 | CYP11B1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2365970-B1 | PYRIDAZINONES AND THEIR USE AS BTK INHIBITORS | GILEAD CONNECTICUT INC (US) | 2018-03-21 | — | — | EP | disclosed |