Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21183528 | 0.83 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1KDM4EP2RX7LMNA | |
| SCHEMBL19982897 | 0.80 | CTSL (0.52) | SMN1; SMN2ALDH1A1CTSLCTSBCTSK | |
| SCHEMBL19982724 | 0.73 | ALDH1A1 (0.37) | SMN1; SMN2ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL19974800 | 0.72 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1KDM4EP2RX7LMNA | |
| SCHEMBL19974935 | 0.70 | HPGD (0.44) | SMN1; SMN2ALDH1A1KDM4EP2RX7MAPT | |
| SCHEMBL19974926 | 0.69 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1KDM4EP2RX7LMNA | |
| SCHEMBL19974961 | 0.69 | POLB (0.45) | SMN1; SMN2ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL19975412 | 0.67 | HPGD (0.49) | SMN1; SMN2ALDH1A1KDM4EP2RX7LMNA | |
| SCHEMBL28316787 | 0.67 | F10 (0.41) | SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL5526076 | 0.67 | CTSS (0.74) | SMN1; SMN2CTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050631-A1 | ANTIVIRAL COMPOUNDS | HAPLOGEN GMBH (AT) | 2018-03-22 | — | — | WO | disclosed |