Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 9/20 | 0.52 |
| ▸ | CTSK | P43235 | 5/20 | 0.52 |
| ▸ | CTSB | P07858 | 5/20 | 0.52 |
| ▸ | CTSS | P25774 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 5/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19974729 | 0.82 | ALDH1A1 (0.50) | CTSLCTSKCTSBCTSSSMN1; SMN2 | |
| SCHEMBL19975354 | 0.80 | ALDH1A1 (0.53) | CTSLCTSKCTSBCTSSSMN1; SMN2 | |
| SCHEMBL19982723 | 0.80 | SMN1; SMN2 (0.52) | CTSLCTSKCTSBSMN1; SMN2ALDH1A1 | |
| SCHEMBL21176167 | 0.79 | ALDH1A1 (0.55) | CTSLCTSKCTSBCTSSSMN1; SMN2 | |
| SCHEMBL19975275 | 0.77 | F10 (0.47) | CTSLCTSKCTSBCTSSSMN1; SMN2 | |
| SCHEMBL8393362 | 0.75 | SMN1; SMN2 (0.68) | CTSLCTSKCTSBSMN1; SMN2HDAC3 | |
| SCHEMBL19975200 | 0.75 | F10 (0.48) | CTSLCTSKCTSBCTSSSMN1; SMN2 | |
| SCHEMBL19975371 | 0.75 | CTSL (0.46) | CTSLCTSKCTSBCTSSSMN1; SMN2 | |
| SCHEMBL19974854 | 0.73 | GPR88 (0.45) | CTSLCTSKCTSBCTSSSMN1; SMN2 | |
| SCHEMBL8391563 | 0.72 | SMN1; SMN2 (0.73) | CTSLCTSKCTSBSMN1; SMN2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050631-A1 | ANTIVIRAL COMPOUNDS | HAPLOGEN GMBH (AT) | 2018-03-22 | — | — | WO | disclosed |