Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983185 | 0.78 | ALDH1A1 (0.40) | ALDH1A1LMNA | |
| SCHEMBL15160145 | 0.75 | — | — | |
| SCHEMBL19983219 | 0.73 | — | — | |
| SCHEMBL19982889 | 0.72 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL15088747 | 0.72 | CES2 (0.43) | FDPS | |
| SCHEMBL19861724 | 0.71 | ALDH1A1 (0.46) | ALDH1A1LMNAFDPS | |
| SCHEMBL25382283 | 0.71 | ALDH1A1 (0.41) | ALDH1A1LMNA | |
| SCHEMBL11861735 | 0.71 | LMNA (0.48) | ALDH1A1LMNAFDPS | |
| SCHEMBL15508644 | 0.70 | CES2 (0.46) | FDPS | |
| SCHEMBL21505107 | 0.70 | CES2 (0.46) | FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2881394-B1 | CONDENSED RING HETEROCYCLIC COMPOUND | KYOWA HAKKO KIRIN CO LTD (JP) | 2018-03-21 | — | — | EP | disclosed |