Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 4/20 | 0.33 |
| ▸ | RORC | P51449 | 3/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
| ▸ | PDE5A | O76074 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16626638 | 0.84 | RORC (0.47) | SOS1METAP2RORCPDE4APDE4B | |
| SCHEMBL16618918 | 0.75 | RORC (0.51) | METAP2RORCPDE4APDE4BPDE4C | |
| SCHEMBL16626632 | 0.67 | RORC (0.49) | METAP2RORCPDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL16619315 | 0.67 | RORC (0.49) | METAP2RORCPDE4APDE4BPDE4C | |
| SCHEMBL28068082 | 0.67 | RORC (0.49) | METAP2RORCPDE4APDE4BPDE4C | |
| SCHEMBL19971362 | 0.66 | RORC (0.48) | METAP2RORCPDE4APDE4BPDE4C | |
| SCHEMBL2408757 | 0.66 | SOS1 (0.41) | SOS1PDK2 | |
| SCHEMBL16626634 | 0.65 | RORC (0.45) | SOS1RORC | |
| SCHEMBL2407583 | 0.62 | SOS1 (0.36) | SOS1DHODHPDK2 | |
| SCHEMBL24884120 | 0.61 | GPER1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |