Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.47 |
| ▸ | SNCA | P37840 | 8/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983786 | 0.82 | SLC6A4 (0.43) | GPR84SNCASLC6A4KCNH2HTR2A | |
| SCHEMBL19983905 | 0.80 | GPR84 (0.45) | GPR84SNCASLC6A4KCNH2HTR2A | |
| SCHEMBL19984039 | 0.78 | GPR84 (0.50) | GPR84SNCASLC6A4KCNH2HTR2A | |
| SCHEMBL19984218 | 0.77 | SLC6A4 (0.39) | GPR84SLC6A4KCNH2HTR2ASLC6A2 | |
| SCHEMBL13452639 | 0.77 | SLC6A4 (0.58) | SLC6A4KCNH2HTR2ASLC6A2SLC6A3 | |
| SCHEMBL19983829 | 0.76 | HTR2A (0.44) | GPR84SNCASLC6A4KCNH2HTR2A | |
| SCHEMBL19983972 | 0.75 | GPR84 (0.40) | GPR84SLC6A4HTR2ACYP3A4CYP2C19 | |
| SCHEMBL19983976 | 0.74 | GPR84 (0.40) | GPR84SLC6A4HTR2ACYP3A4CYP2C19 | |
| SCHEMBL19984023 | 0.74 | HTR2A (0.47) | GPR84SLC6A4HTR2ASLC6A2SLC6A3 | |
| SCHEMBL19983801 | 0.74 | GPR84 (0.41) | GPR84SLC6A4HTR2ACYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |