Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.50 |
| ▸ | MPO | P05164 | 3/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.41 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.41 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983829 | 0.86 | HTR2A (0.44) | GPR84HTR2ASLC6A2SLC6A3SLC6A4 | |
| SCHEMBL19983786 | 0.85 | SLC6A4 (0.43) | GPR84HTR2ASLC6A2SLC6A3SLC6A4 | |
| SCHEMBL31415127 | 0.83 | GPR84 (0.72) | GPR84MPOHTR2AHTR1AHTR6 | |
| SCHEMBL19984218 | 0.82 | SLC6A4 (0.39) | GPR84HTR2ASLC6A2SLC6A3SLC6A4 | |
| SCHEMBL19983801 | 0.79 | GPR84 (0.41) | GPR84MPOHTR2ASLC6A2SLC6A3 | |
| SCHEMBL19984023 | 0.79 | HTR2A (0.47) | GPR84MPOHTR2ASLC6A2SLC6A3 | |
| SCHEMBL19984030 | 0.79 | GPR84 (0.48) | GPR84MPOHTR2ASLC6A2SLC6A3 | |
| SCHEMBL19984036 | 0.79 | LMNA (0.44) | GPR84HTR2ASLC6A2SLC6A3SLC6A4 | |
| SCHEMBL19983972 | 0.78 | GPR84 (0.40) | GPR84HTR2ASLC6A2SLC6A3SLC6A4 | |
| SCHEMBL19983967 | 0.78 | GPR84 (0.47) | GPR84HTR2ASLC6A2SLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |