Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.41 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.40 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983829 | 0.85 | HTR2A (0.44) | HTR2AGPR84PCSK9ALKBH5FTO | |
| SCHEMBL19984036 | 0.85 | LMNA (0.44) | HTR2AGPR84CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19984035 | 0.84 | HTR2A (0.47) | HTR2AGPR84PCSK9ALKBH5FTO | |
| SCHEMBL19983801 | 0.82 | GPR84 (0.41) | HTR2AGPR84CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL3281375 | 0.82 | HTR2A (0.61) | HTR2AGPR84PCSK9ALKBH5FTO | |
| SCHEMBL19984044 | 0.81 | GPR84 (0.40) | HTR2AGPR84CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19984283 | 0.80 | HTR2A (0.47) | HTR2AGPR84PCSK9ALKBH5FTO | |
| SCHEMBL19984039 | 0.79 | GPR84 (0.50) | HTR2AGPR84ALKBH5FTOMPO | |
| SCHEMBL19983754 | 0.78 | HTR2A (0.45) | HTR2AGPR84PCSK9ALKBH5FTO | |
| SCHEMBL19983976 | 0.76 | GPR84 (0.40) | HTR2AGPR84PCSK9CHRNB2CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |