Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PNP | P00491 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983976 | 0.89 | GPR84 (0.40) | GPR84SLC6A4SLC6A2SLC6A3CHRNB2 | |
| SCHEMBL19983815 | 0.86 | CYP2C9 (0.43) | GPR84SLC6A4SLC6A2SLC6A3CHRNB2 | |
| SCHEMBL19983829 | 0.79 | HTR2A (0.44) | GPR84SLC6A4SLC6A2SLC6A3CHRNB2 | |
| SCHEMBL19983894 | 0.79 | GPR84 (0.39) | GPR84SLC6A4CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19984039 | 0.78 | GPR84 (0.50) | GPR84SLC6A4SLC6A2SLC6A3HTR1A | |
| SCHEMBL19984044 | 0.77 | GPR84 (0.40) | GPR84CHRNB2CHRNA7CHRNA4CYP3A4 | |
| SCHEMBL19983786 | 0.75 | SLC6A4 (0.43) | GPR84SLC6A4SLC6A2SLC6A3CHRNB2 | |
| SCHEMBL19983967 | 0.75 | GPR84 (0.47) | GPR84SLC6A4SLC6A2SLC6A3CHRNB2 | |
| SCHEMBL19984035 | 0.75 | HTR2A (0.47) | GPR84CHRNB2CHRNA7CHRNA4ASH1L | |
| SCHEMBL19984023 | 0.74 | HTR2A (0.47) | GPR84SLC6A4SLC6A2SLC6A3CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |