Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 16/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 13/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983804 | 0.89 | EPHX2 (0.37) | GRIN2BGRIN1METAP2EPHX2PRMT6 | |
| SCHEMBL19984210 | 0.85 | PRMT6 (0.40) | METAP2EPHX2PRMT6 | |
| SCHEMBL19984162 | 0.85 | PRMT6 (0.40) | METAP2EPHX2PRMT6 | |
| SCHEMBL19983805 | 0.83 | EPHX2 (0.34) | EPHX2PRMT6 | |
| SCHEMBL19984196 | 0.83 | PRMT6 (0.36) | METAP2EPHX2PRMT6 | |
| SCHEMBL19983914 | 0.83 | FYN (0.37) | GRM5EPHX2PRMT6 | |
| SCHEMBL17971569 | 0.79 | GRIN2B (0.39) | GRIN2BGRIN1METAP2 | |
| SCHEMBL16626086 | 0.79 | GRIN2B (0.38) | GRIN2BGRIN1METAP2GRM5PIK3CB | |
| Hydrochloric Acid SCHEMBL16618679 | 0.78 | GRIN2B (0.39) | GRIN2BGRIN1METAP2 | |
| SCHEMBL19983826 | 0.78 | ABCG2 (0.37) | METAP2EPHX2PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |