Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984210 | 1.00 | PRMT6 (0.40) | PRMT6EPHX2HTR6NR1D1HTR2C | |
| SCHEMBL19984196 | 0.92 | PRMT6 (0.36) | PRMT6EPHX2HTR6NR1D1HTR2C | |
| SCHEMBL19983804 | 0.88 | EPHX2 (0.37) | PRMT6EPHX2NR1D1METAP2CLK4 | |
| SCHEMBL19983805 | 0.86 | EPHX2 (0.34) | PRMT6EPHX2NR1D1CYP2C19CYP2D6 | |
| SCHEMBL19984177 | 0.85 | HTR2C (0.39) | PRMT6EPHX2HTR6HTR2CMETAP2 | |
| SCHEMBL19983914 | 0.85 | FYN (0.37) | PRMT6EPHX2NR1D1CYP2C19CYP2D6 | |
| SCHEMBL19984032 | 0.85 | GRIN2B (0.39) | PRMT6EPHX2METAP2 | |
| SCHEMBL19983721 | 0.79 | HTR2C (0.32) | HTR6HTR2CMETAP2 | |
| SCHEMBL19983848 | 0.78 | MAP3K8 (0.32) | PRMT6EPHX2HTR2CMETAP2 | |
| SCHEMBL19984241 | 0.78 | RAPGEF4 (0.32) | HTR2CALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |