Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.34 |
| ▸ | CDK2 | P24941 | 2/20 | 0.34 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 2/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.30 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984210 | 0.92 | PRMT6 (0.40) | PRMT6EPHX2CCNE1CDK2NR1D1 | |
| SCHEMBL19984162 | 0.92 | PRMT6 (0.40) | PRMT6EPHX2CCNE1CDK2NR1D1 | |
| SCHEMBL19983804 | 0.86 | EPHX2 (0.37) | PRMT6EPHX2NR1D1METAP2 | |
| SCHEMBL19983805 | 0.84 | EPHX2 (0.34) | PRMT6EPHX2NR1D1CYP2D6CYP2C9 | |
| SCHEMBL19983914 | 0.84 | FYN (0.37) | PRMT6EPHX2NR1D1CYP2D6CYP2C19 | |
| SCHEMBL19984032 | 0.83 | GRIN2B (0.39) | PRMT6EPHX2METAP2 | |
| SCHEMBL19984177 | 0.80 | HTR2C (0.39) | PRMT6EPHX2HTR6METAP2AXL | |
| SCHEMBL19983883 | 0.78 | HTR2C (0.32) | HTR2C | |
| SCHEMBL19983727 | 0.77 | ABL1 (0.36) | CYP2C9CYP2C19HTR2CMEN1 | |
| SCHEMBL19984241 | 0.77 | RAPGEF4 (0.32) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |