Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983805 | 0.90 | EPHX2 (0.34) | EPHX2PRMT6CYP19A1USP2LMNA | |
| SCHEMBL19983804 | 0.88 | EPHX2 (0.37) | EPHX2PRMT6MAPTPDE5ANR1D1 | |
| SCHEMBL19984162 | 0.85 | PRMT6 (0.40) | EPHX2PRMT6USP2LMNACYP1A2 | |
| SCHEMBL19984210 | 0.85 | PRMT6 (0.40) | EPHX2PRMT6USP2LMNACYP1A2 | |
| SCHEMBL19984196 | 0.84 | PRMT6 (0.36) | EPHX2PRMT6CYP2D6CYP2C19NR4A2 | |
| SCHEMBL19984032 | 0.83 | GRIN2B (0.39) | EPHX2PRMT6GRM5 | |
| SCHEMBL19984298 | 0.81 | NR4A2 (0.50) | PIK3CAPIK3CGHSD17B1HSD17B2CYP19A1 | |
| SCHEMBL16619135 | 0.78 | HTR6 (0.38) | FYNPIK3CAPIK3CGEPHX2PRMT6 | |
| SCHEMBL19983840 | 0.78 | LRRK2 (0.36) | JAK2TYK2JAK3 | |
| SCHEMBL19984177 | 0.76 | HTR2C (0.39) | EPHX2PRMT6CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |