Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16626433 | 0.89 | EGFR (0.33) | EGFR | |
| SCHEMBL19984136 | 0.86 | MEN1 (0.39) | EGFR | |
| SCHEMBL16626499 | 0.85 | DOT1L (0.31) | EGFR | |
| SCHEMBL16626693 | 0.85 | TBXAS1 (0.31) | ALDH1A1EGFRTBXAS1 | |
| SCHEMBL16626424 | 0.85 | MAPK14 (0.36) | ALDH1A1TBXAS1 | |
| SCHEMBL19984086 | 0.85 | EGFR (0.34) | EGFR | |
| SCHEMBL16626477 | 0.84 | — | — | |
| SCHEMBL16626468 | 0.84 | METAP2 (0.30) | — | |
| SCHEMBL19984004 | 0.84 | MEN1 (0.32) | ALDH1A1 | |
| SCHEMBL16626457 | 0.84 | PARP14 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |