Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 8/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 6/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983898 | 0.88 | CHRNB2 (0.38) | CYP2C19CYP3A4GPR84EGFRIMPDH2 | |
| SCHEMBL19983903 | 0.87 | CYP2D6 (0.39) | CYP2D6CYP1A2CYP2C8CYP2C19KCNH2 | |
| SCHEMBL19984195 | 0.85 | LRRK2 (0.41) | CYP2C19CYP2C9CYP3A4IMPDH2PTGS2 | |
| SCHEMBL19983877 | 0.82 | GPR84 (0.36) | GPR84PTGS2CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19983728 | 0.81 | CHRNB2 (0.39) | CYP2D6CYP1A2CYP2C8CYP2C19KCNH2 | |
| SCHEMBL19983880 | 0.79 | MEN1 (0.36) | GPR84PTGS2CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19984234 | 0.78 | BCL6 (0.38) | CYP2D6CYP1A2CYP2C8CYP2C19KCNH2 | |
| SCHEMBL16626544 | 0.78 | GPR84 (0.36) | CYP2C9GPR84CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19983861 | 0.76 | GPR84 (0.41) | CYP2D6CYP1A2CYP2C8CYP2C19KCNH2 | |
| SCHEMBL19984001 | 0.75 | MAPK8 (0.48) | GPR84HTR1ASLC6A2PTGS2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |