Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.34 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | PAK4 | O96013 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983877 | 0.88 | GPR84 (0.36) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL19983771 | 0.88 | CHRNB2 (0.38) | KDM4EALDH1A1ADORA2AHTR2ACHRNB2 | |
| SCHEMBL19983913 | 0.84 | GPR84 (0.38) | ADORA2AHTR2ACHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19984013 | 0.83 | HTR2A (0.35) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL19984195 | 0.83 | LRRK2 (0.41) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL19984215 | 0.80 | GAA (0.47) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL16626544 | 0.80 | GPR84 (0.36) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL19983898 | 0.79 | CHRNB2 (0.38) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL19984147 | 0.79 | CYP2D6 (0.36) | HTR2ACHRNB2CHRNA7CHRNA4PTGS2 | |
| SCHEMBL19984194 | 0.79 | GPR84 (0.39) | KDM4EALDH1A1HTR2ACHRNB2CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |