Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 4/20 | 0.35 |
| ▸ | FPR1 | P21462 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984132 | 0.87 | HDAC11 (0.31) | — | |
| SCHEMBL19984009 | 0.85 | ALPL (0.37) | — | |
| SCHEMBL19983893 | 0.84 | HTR2C (0.32) | — | |
| SCHEMBL19983814 | 0.84 | — | — | |
| SCHEMBL19983879 | 0.83 | — | — | |
| SCHEMBL19984177 | 0.82 | HTR2C (0.39) | — | |
| SCHEMBL19983733 | 0.82 | SLC6A2 (0.37) | P2RX7 | |
| SCHEMBL19983883 | 0.82 | HTR2C (0.32) | P2RX7 | |
| SCHEMBL19983721 | 0.82 | HTR2C (0.32) | — | |
| SCHEMBL19984171 | 0.81 | POLB (0.37) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |