Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | MAT2A | P31153 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984127 | 0.91 | NUDT1 (0.36) | SLC6A2SLC6A4MAT2ACYP11B1CYP11B2 | |
| SCHEMBL19984171 | 0.91 | POLB (0.37) | SLC6A2POLBNAMPTP2RX7HTR2C | |
| SCHEMBL19983883 | 0.91 | HTR2C (0.32) | SLC6A2SLC6A4P2RX7HTR2CFLT1 | |
| SCHEMBL19983850 | 0.90 | LRRK2 (0.40) | SLC6A4SRCCNR2 | |
| SCHEMBL19983740 | 0.90 | CYP11B1 (0.35) | SLC6A2SLC6A4MAPTSRCMAT2A | |
| SCHEMBL19984087 | 0.89 | SLC6A2 (0.34) | SLC6A2SLC6A4HTR2C | |
| SCHEMBL19983727 | 0.88 | ABL1 (0.36) | SLC6A2SLC6A4MEN1MAPTKMT2A | |
| SCHEMBL19983736 | 0.88 | MAPT (0.38) | MEN1MAPTKMT2ACYP1A2CYP2D6 | |
| SCHEMBL19984135 | 0.87 | BCL6 (0.40) | MAPTSRCCNR2CYP11B1CYP11B2 | |
| SCHEMBL19983743 | 0.86 | SRC (0.40) | SLC6A2SLC6A4SRCFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |