Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | BCL6 | P41182 | 3/20 | 0.31 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.31 |
| ▸ | FLT1 | P17948 | 1/20 | 0.30 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983743 | 0.91 | SRC (0.40) | FLT1EPHA2KDREPHB4SLC6A2 | |
| SCHEMBL19983733 | 0.91 | SLC6A2 (0.37) | HTR2CFLT1P2RX7SLC6A2SLC6A4 | |
| SCHEMBL19984171 | 0.89 | POLB (0.37) | HTR2CBCL6P2RX7EGFRSLC6A2 | |
| SCHEMBL19983850 | 0.88 | LRRK2 (0.40) | BCL6SLC6A4 | |
| SCHEMBL19984087 | 0.87 | SLC6A2 (0.34) | HTR2CEGFRSLC6A2SLC6A4 | |
| SCHEMBL19983727 | 0.86 | ABL1 (0.36) | HTR2CSLC6A2SLC6A4 | |
| SCHEMBL19984127 | 0.86 | NUDT1 (0.36) | FLT1KDREGFRSLC6A2SLC6A4 | |
| SCHEMBL19983736 | 0.86 | MAPT (0.38) | BCL6BCOR | |
| SCHEMBL19984177 | 0.85 | HTR2C (0.39) | HTR2C | |
| SCHEMBL19983721 | 0.85 | HTR2C (0.32) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |