SCHEMBL19983893

SCHEMBL19983893

CNCc1cn(Sc2cccnc2)c2cc(Nc3cncc(Br)c3)ccc12

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 1/20 0.32
METAP2 P50579 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19984177 0.88 HTR2C (0.39) HTR2CMETAP2
SCHEMBL19983727 0.84 ABL1 (0.36) HTR2C
SCHEMBL19983826 0.84 ABCG2 (0.37) HTR2CMETAP2
SCHEMBL19984186 0.84 P2RX7 (0.35)
SCHEMBL19984241 0.82 RAPGEF4 (0.32) HTR2C
SCHEMBL19983848 0.82 MAP3K8 (0.32) HTR2CMETAP2
SCHEMBL19983879 0.82
SCHEMBL19984132 0.82 HDAC11 (0.31) METAP2
SCHEMBL19983814 0.81
SCHEMBL19984199 0.81 MAP3K8 (0.31) HTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3052484-B1 SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME DAE WOONG PHARMA (KR) 2018-03-21 EP disclosed