Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2586861 | 0.77 | NOX1 (0.55) | GAAMAPTIDO1L3MBTL1ADORA3 | |
| SCHEMBL20594006 | 0.72 | SMN1; SMN2 (0.48) | GAAMAPTL3MBTL1 | |
| SCHEMBL7220824 | 0.71 | ALDH1A1 (0.48) | GAAMAPTL3MBTL1 | |
| Acetic Acid SCHEMBL27908975 | 0.70 | NOX1 (0.51) | GAAMAPTL3MBTL1ADORA3 | |
| SCHEMBL7888523 | 0.69 | MAPT (0.79) | GAAMAPTIDO1L3MBTL1ADORA3 | |
| SCHEMBL19984562 | 0.63 | MAPT (0.34) | GAAMAPTIDO1L3MBTL1 | |
| SCHEMBL23018616 | 0.62 | L3MBTL1 (0.54) | GAAMAPTL3MBTL1 | |
| SCHEMBL19984763 | 0.62 | L3MBTL1 (0.68) | GAAMAPTIDO1L3MBTL1ADORA3 | |
| SCHEMBL12396548 | 0.62 | GAA (0.81) | GAAMAPTIDO1L3MBTL1ADORA3 | |
| SCHEMBL21101750 | 0.61 | NOX1 (0.52) | GAAMAPTIDO1L3MBTL1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6583138-B1 | Mediators or antagonists of the effects of histamine, leukotriene and the like; heterocyclic ring condensed benzothiazine compounds; inhibit the activation of the tyrosine kinase of 72 kDa | EISAI CO., LTD. (JP) | 2003-06-24 | — | — | US | disclosed |
| EP-1057830-A1 | HETEROCYCLE-FUSED BENZOTHIAZINE DERIVATIVES | Eisai Co., Ltd. (JP) | 2000-12-06 | — | — | EP | disclosed |