SCHEMBL19984637

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19984601	0.83	RAB9A (0.38)	RAB9APOLBEPHX2PPARGROCK2
	SCHEMBL19984584	0.82	PDE4A (0.47)	RAB9AROCK2NPC1ALDH1A1HPGD
	SCHEMBL21273273	0.75	TNKS2 (0.42)	RAB9APOLBROCK2NPC1ALDH1A1
	SCHEMBL19984583	0.72	AR (0.39)	RAB9APOLBROCK2NPC1ALDH1A1
	SCHEMBL1173806	0.70	KMO (0.47)	APPPOLBF10ALDH1A1HPGD
	SCHEMBL13965798	0.69	ADRA1D (0.43)	HTR1DHTR1BAPPKCNH2POLB
	SCHEMBL19984748	0.69	SMYD3 (0.41)	—
	SCHEMBL1173489	0.69	KMO (0.44)	APPPOLBF10ALDH1A1HPGD
	SCHEMBL51234	0.69	NPC1 (0.53)	APPRAB9APOLBCCR2NPC1
	SCHEMBL1173868	0.67	NPC1 (0.54)	APPRAB9APOLBNPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.