Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | PARP1 | P09874 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984752 | 0.96 | PARP1 (0.41) | ALDH1A1KDM4EMAPTGAAPARP1 | |
| SCHEMBL19984539 | 0.78 | HSD17B10 (0.59) | ALDH1A1GAAPARP1KMT2ASMN1; SMN2 | |
| SCHEMBL19984617 | 0.74 | HTT (0.62) | ALDH1A1KDM4EMAPTGAAKMT2A | |
| SCHEMBL19984542 | 0.73 | ALDH1A1 (0.40) | ALDH1A1KDM4EMAPTGAAPARP1 | |
| SCHEMBL6540956 | 0.71 | KMT2A (0.66) | ALDH1A1KDM4EMAPTGAAPARP1 | |
| SCHEMBL31694053 | 0.71 | KMT2A (0.66) | ALDH1A1KDM4EMAPTGAAPARP1 | |
| SCHEMBL19984618 | 0.69 | KMT2A (0.39) | ALDH1A1KDM4EMAPTGAAPARP1 | |
| SCHEMBL10281626 | 0.64 | ALDH1A1 (0.72) | ALDH1A1KDM4EMAPTGAAPARP1 | |
| SCHEMBL708740 | 0.64 | ALDH1A1 (0.72) | ALDH1A1KDM4EMAPTGAAPARP1 | |
| SCHEMBL22278441 | 0.63 | KMT2A (0.48) | ALDH1A1KDM4EMAPTGAAPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018053157-A1 | HEPATITIS B CORE PROTEIN MODULATORS | ASSEMBLY BIOSCIENCES, INC. (US) | 2018-03-22 | — | — | WO | disclosed |