Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984716 | 0.96 | ALDH1A1 (0.41) | PARP1KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL19984539 | 0.81 | HSD17B10 (0.59) | PARP1KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL19984617 | 0.78 | HTT (0.62) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL19984618 | 0.73 | KMT2A (0.39) | PARP1KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL19984542 | 0.69 | ALDH1A1 (0.40) | PARP1KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL31694053 | 0.68 | KMT2A (0.66) | PARP1KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL6540956 | 0.68 | KMT2A (0.66) | PARP1KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL16099830 | 0.63 | OPRM1 (0.41) | — | |
| SCHEMBL22278441 | 0.62 | KMT2A (0.48) | PARP1KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL30660976 | 0.62 | KMT2A (0.48) | PARP1KMT2AMEN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018053157-A1 | HEPATITIS B CORE PROTEIN MODULATORS | ASSEMBLY BIOSCIENCES, INC. (US) | 2018-03-22 | — | — | WO | disclosed |