Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 4/20 | 0.55 |
| ▸ | ADAMTS5 | Q9UNA0 | 4/20 | 0.55 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CTSA | P10619 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984825 | 0.97 | ADAMTS4 (0.57) | ADAMTS4ADAMTS5PPARDCTSSCTSK | |
| SCHEMBL19984967 | 0.94 | ADAMTS4 (0.54) | ADAMTS4ADAMTS5PPARDCTSSCTSK | |
| SCHEMBL19984985 | 0.90 | ADAMTS4 (0.55) | ADAMTS4ADAMTS5CTSSCTSKHPGD | |
| SCHEMBL19984846 | 0.86 | PPARD (0.49) | PPARDKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19984971 | 0.79 | ADAMTS4 (0.45) | ADAMTS4ADAMTS5PPARDKMT2ANPC1 | |
| SCHEMBL18078747 | 0.78 | ADAMTS4 (0.45) | ADAMTS4ADAMTS5CTSSCTSKKMT2A | |
| SCHEMBL19866363 | 0.78 | ADAMTS4 (0.45) | ADAMTS4ADAMTS5CTSSCTSKKMT2A | |
| SCHEMBL19984799 | 0.76 | KMT2A (0.43) | ADAMTS4ADAMTS5CTSSCTSKKMT2A | |
| SCHEMBL19984976 | 0.76 | APLNR (0.54) | PPARDKMT2AHPGDMAPK1MAPT | |
| SCHEMBL19984851 | 0.74 | CTSS (0.43) | ADAMTS4ADAMTS5CTSSCTSKKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018051255-A1 | CYCLIC SUBSTITUTED-1,3,4-OXADIAZOLE AND THIADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-03-22 | — | — | WO | disclosed |