Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TERT | O14746 | 4/20 | 0.38 |
| ▸ | PIEZO1 | Q92508 | 10/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26777790 | 0.76 | KDM4E (0.48) | KDM4ETERTPIEZO1HSD17B10CYP2D6 | |
| SCHEMBL19984983 | 0.70 | KDM4E (0.47) | KDM4ETERTPIEZO1HSD17B10MEN1 | |
| SCHEMBL19984852 | 0.65 | KDM4E (0.37) | KDM4ETERTPIEZO1HSD17B10MEN1 | |
| SCHEMBL15599488 | 0.64 | KDM4E (0.50) | KDM4ETERTPIEZO1HSD17B10MEN1 | |
| SCHEMBL19984805 | 0.63 | NPY5R (0.37) | KDM4ETERTPIEZO1MEN1ALDH1A1 | |
| SCHEMBL579479 | 0.61 | KDM4E (0.47) | KDM4ETERTPIEZO1HSD17B10MEN1 | |
| SCHEMBL16997502 | 0.61 | KDM4E (0.47) | KDM4ETERTPIEZO1HSD17B10MEN1 | |
| SCHEMBL26671383 | 0.61 | KDM4E (0.47) | KDM4ETERTPIEZO1HSD17B10MEN1 | |
| SCHEMBL18490869 | 0.59 | RAB9A (0.62) | KDM4EHSD17B10CYP2C19MEN1ALDH1A1 | |
| SCHEMBL10563043 | 0.59 | TERT (0.56) | KDM4ETERTPIEZO1HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018051255-A1 | CYCLIC SUBSTITUTED-1,3,4-OXADIAZOLE AND THIADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-03-22 | — | — | WO | disclosed |