Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | PKM | P14618 | 6/20 | 0.55 |
| ▸ | THRB | P10828 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984829 | 0.79 | LMNA (0.50) | LMNAPOLBPKMTHRBMEN1 | |
| SCHEMBL19984828 | 0.73 | TP53 (0.47) | LMNAMEN1KMT2A | |
| SCHEMBL10154069 | 0.66 | PKM (0.66) | LMNAPOLBPKMTHRBMEN1 | |
| SCHEMBL19984993 | 0.65 | PTK2 (0.48) | LMNATHRBKMT2A | |
| SCHEMBL19984797 | 0.64 | KMT2A (0.44) | LMNATHRBMEN1KMT2A | |
| SCHEMBL19984784 | 0.64 | PTK2 (0.47) | LMNATHRBMEN1KMT2A | |
| SCHEMBL29411450 | 0.64 | PKM (0.66) | LMNAPOLBPKMTHRBMEN1 | |
| SCHEMBL21045103 | 0.64 | PKM (0.66) | LMNAPOLBPKMTHRBMEN1 | |
| SCHEMBL13073875 | 0.64 | PTK2 (0.59) | LMNATHRBMEN1KMT2A | |
| SCHEMBL19984808 | 0.64 | EGFR (0.50) | LMNATHRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018051255-A1 | CYCLIC SUBSTITUTED-1,3,4-OXADIAZOLE AND THIADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-03-22 | — | — | WO | disclosed |