SCHEMBL19984888

SCHEMBL19984888

CC1CCC(NCCC#N)CC1NCCC#N

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
JAK1 P23458 2/20 0.31
JAK2 O60674 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12424641 0.80 TSHR (0.38) JAK1JAK2
SCHEMBL23889394 0.77 TSHR (0.36) JAK1JAK2
SCHEMBL1190555 0.77
SCHEMBL5831087 0.77 JAK1 (0.39) JAK1JAK2
SCHEMBL5079431 0.77 KDM1A (0.37)
SCHEMBL19984667 0.77 ALDH1A1 (0.37)
SCHEMBL28947585 0.77 ALDH1A1 (0.34) JAK2
SCHEMBL21782065 0.76 ALDH1A1 (0.38) JAK1JAK2
SCHEMBL15014481 0.76 ALDH1A1 (0.38) JAK1JAK2
SCHEMBL20240511 0.74 SQLE (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3515898-B1 PROCESS FOR THE PREPARATION OF POLYAMINES STARTING FROM DINITRILES AND/OR AMINONITRILES BASF SE (DE) 2020-11-11 EP disclosed
US-20190218341-A1 METHOD FOR THE PREPARATION OF POLYAMINES FROM DINITRILES AND/OR AMINO NITRILES BASF SE (DE) 2019-07-18 US disclosed
WO-2018050554-A1 CYANOETHYLATED METHYLCYCLOHEXANE DIAMINE (MCDA) AND TOLUENE DIAMINE (TDA) DERIVATIVES BASF SE (DE) 2018-03-22 WO disclosed
WO-2018050555-A1 METHOD FOR THE PREPARATION OF POLYAMINES FROM DINITRILES AND/OR AMINO NITRILES BASF SE (DE) 2018-03-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190218341-A1 METHOD FOR THE PREPARATION OF POLYAMINES FROM DINITRILES AND/OR AMINO NITRILES SRM, PRMT1, HNMT JAK1 3077/4885JAK2 2328/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.