Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.55 |
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.51 |
| ▸ | MIF | P14174 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.49 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.49 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | STAT1 | P42224 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19994122 | 0.84 | ALDH1A1 (0.55) | MAPTPTP4A1MIFALDH1A1PDCD1 | |
| SCHEMBL28296981 | 0.84 | ALDH1A1 (0.55) | MAPTPTP4A1MIFALDH1A1PDCD1 | |
| SCHEMBL19994120 | 0.84 | ALDH1A1 (0.55) | MAPTPTP4A1MIFALDH1A1PDCD1 | |
| SCHEMBL12677356 | 0.77 | ALDH1A1 (0.69) | MAPTPTP4A1MIFALDH1A1PDCD1 | |
| SCHEMBL17351447 | 0.75 | MAPT (0.76) | MAPTPTP4A1MIFALDH1A1PDCD1 | |
| SCHEMBL17351448 | 0.75 | MAPT (0.76) | MAPTPTP4A1MIFALDH1A1PDCD1 | |
| SCHEMBL12677357 | 0.73 | MAPT (0.61) | MAPTMIFALDH1A1PDCD1CD274 | |
| SCHEMBL12670733 | 0.73 | MAPT (0.61) | MAPTMIFALDH1A1PDCD1CD274 | |
| SCHEMBL17351445 | 0.73 | MAPT (0.61) | MAPTMIFALDH1A1PDCD1CD274 | |
| SCHEMBL13559199 | 0.73 | MIF (0.76) | MAPTPTP4A1MIFALDH1A1PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180078541-A1 | 6-MEMBERED CYCLIC AMINES OR LACTAMES SUBSTITUTED WITH UREA AND PHENYL | Grünenthal GmbH (DE) | 2018-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180078541-A1 | 6-MEMBERED CYCLIC AMINES OR LACTAMES SUBSTITUTED WITH UREA AND PHENYL | FPR2, FPR1, FPR3 | MAPT 4276/4885PTP4A1 4498/4885MIF 212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.