SCHEMBL19986434

SCHEMBL19986434

c1ccc(-c2ccc3oc4cc5oc6c(-c7ccccc7)cc(-c7ccc8c(c7)c7ccccc7n8-c7ccccc7)cc6c5cc4c3c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.39
KDM4E B2RXH2 1/20 0.39
ATM Q13315 1/20 0.39
PLA2G2A P14555 3/20 0.34
PLA2G4A P47712 3/20 0.34
ALDH1A1 P00352 3/20 0.34
KMT2A Q03164 3/20 0.34
MEN1 O00255 2/20 0.34
POLB P06746 1/20 0.34
TSHR P16473 1/20 0.34
BRCA1 P38398 1/20 0.34
HSD17B10 Q99714 1/20 0.34
PRKDC P78527 3/20 0.33
TSPO P30536 1/20 0.33
SIRT2 Q8IXJ6 1/20 0.32
SIRT1 Q96EB6 1/20 0.32
PIM1 P11309 1/20 0.32
CSNK2A2 P19784 1/20 0.32
CSNK2B P67870 1/20 0.32
PIM3 Q86V86 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1635846 0.96 KDM4E (0.39) L3MBTL1KDM4EATMPLA2G2APLA2G4A
SCHEMBL10165771 0.93 L3MBTL1 (0.43) L3MBTL1KDM4EATMPLA2G2APLA2G4A
SCHEMBL1637010 0.92 KDM4E (0.40) L3MBTL1KDM4EATMPLA2G2APLA2G4A
SCHEMBL1635239 0.92 KDM4E (0.40) L3MBTL1KDM4EATMPLA2G2APLA2G4A
SCHEMBL17280812 0.91 L3MBTL1 (0.41) L3MBTL1KDM4EATMPLA2G2APLA2G4A
SCHEMBL18020871 0.91 PLA2G2A (0.36) L3MBTL1KDM4EATMPLA2G2APLA2G4A
SCHEMBL16597006 0.91 KDM4E (0.45) L3MBTL1KDM4EATMPLA2G2APLA2G4A
SCHEMBL20706895 0.90 PLA2G2A (0.34) L3MBTL1KDM4EATMPLA2G2APLA2G4A
SCHEMBL22181822 0.90 L3MBTL1 (0.42) L3MBTL1KDM4EATMPLA2G2APLA2G4A
SCHEMBL5028192 0.90 KDM4E (0.42) L3MBTL1KDM4EATMPLA2G2APLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180083205-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2018-03-22 US disclosed
US-20180083205-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2018-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180083205-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME EPCAM, ILK, PPOX L3MBTL1 604/4885KDM4E 2892/4885ATM 1912/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.