Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CNR1 | P21554 | 6/20 | 0.45 |
| ▸ | NAMPT | P43490 | 2/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19986669 | 0.93 | MEN1 (0.48) | MEN1KMT2ACNR1NAMPTSLC2A1 | |
| SCHEMBL19986563 | 0.93 | MEN1 (0.53) | MEN1KMT2ACNR1NAMPTSLC2A1 | |
| SCHEMBL19986553 | 0.90 | KMT2A (0.63) | MEN1KMT2ASLC2A1LMNAMAPT | |
| SCHEMBL19986506 | 0.88 | MEN1 (0.43) | MEN1KMT2ACNR1NAMPTLMNA | |
| SCHEMBL19986566 | 0.86 | MEN1 (0.51) | MEN1KMT2ACNR1NAMPTSLC2A1 | |
| SCHEMBL19986700 | 0.84 | LMNA (0.53) | MEN1KMT2ACNR1NAMPTLMNA | |
| SCHEMBL19986502 | 0.83 | KMT2A (0.60) | MEN1KMT2ASLC2A1LMNAMAPT | |
| SCHEMBL19986628 | 0.81 | MEN1 (0.56) | MEN1KMT2ALMNAMAPTRAB9A | |
| SCHEMBL19986530 | 0.81 | ALOX15 (0.58) | MEN1KMT2ASLC2A1LMNAMAPT | |
| SCHEMBL19986578 | 0.81 | MEN1 (0.41) | MEN1KMT2ACNR1NAMPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113429341-A | Novel capsid protein assembly inhibitors | 正大天晴药业集团股份有限公司 | 2021-09-24 | — | — | CN | disclosed |
| CN-109790123-B | Novel capsid protein assembly inhibitors | 正大天晴药业集团股份有限公司 | 2021-06-25 | — | — | CN | disclosed |
| WO-2018050110-A1 | NOVEL CAPSID PROTEIN ASSEMBLY INHIBITOR | 正大天晴药业集团股份有限公司 | 2018-03-22 | — | — | WO | disclosed |