Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 3/20 | 0.41 |
| ▸ | KCNJ6 | P48051 | 4/20 | 0.38 |
| ▸ | KCNJ5 | P48544 | 4/20 | 0.38 |
| ▸ | KCNJ3 | P48549 | 4/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | LYN | P07948 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19986668 | 0.86 | KCNJ6 (0.39) | BLMNAMPTKCNJ6KCNJ5KCNJ3 | |
| SCHEMBL19986713 | 0.86 | KCNJ6 (0.39) | BLMNAMPTKCNJ6KCNJ5KCNJ3 | |
| SCHEMBL19986464 | 0.75 | BLM (0.44) | BLMNAMPTGRM4MEN1LMNA | |
| SCHEMBL19986517 | 0.73 | KMT2A (0.48) | MEN1LMNAKMT2AMAPTRAB9A | |
| SCHEMBL19986607 | 0.72 | NAMPT (0.41) | BLMNAMPTKCNJ6KCNJ5KCNJ3 | |
| SCHEMBL19986667 | 0.72 | ALDH1A1 (0.48) | MEN1LMNAKMT2AMAPTRAB9A | |
| SCHEMBL19986711 | 0.72 | ALDH1A1 (0.48) | MEN1LMNAKMT2AMAPTRAB9A | |
| SCHEMBL19986694 | 0.72 | NAMPT (0.41) | BLMNAMPTKCNJ6KCNJ5KCNJ3 | |
| SCHEMBL19986634 | 0.69 | KMT2A (0.41) | BLMNAMPTKCNJ6KCNJ5KCNJ3 | |
| SCHEMBL19986603 | 0.67 | NAMPT (0.42) | BLMNAMPTKCNJ6KCNJ5KCNJ3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050110-A1 | NOVEL CAPSID PROTEIN ASSEMBLY INHIBITOR | 正大天晴药业集团股份有限公司 | 2018-03-22 | — | — | WO | disclosed |