Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.41 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | KCNJ6 | P48051 | 4/20 | 0.39 |
| ▸ | KCNJ5 | P48544 | 4/20 | 0.39 |
| ▸ | KCNJ3 | P48549 | 4/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19986607 | 1.00 | NAMPT (0.41) | NAMPTPRMT3KMT2AUSP2KCNJ6 | |
| SCHEMBL19986634 | 0.92 | KMT2A (0.41) | NAMPTPRMT3KMT2AUSP2KCNJ6 | |
| SCHEMBL19986603 | 0.90 | NAMPT (0.42) | NAMPTKMT2AKCNJ6KCNJ5KCNJ3 | |
| SCHEMBL19986713 | 0.86 | KCNJ6 (0.39) | NAMPTKMT2AUSP2KCNJ6KCNJ5 | |
| SCHEMBL19986668 | 0.86 | KCNJ6 (0.39) | NAMPTKMT2AUSP2KCNJ6KCNJ5 | |
| SCHEMBL19986606 | 0.82 | ALDH1A1 (0.53) | KMT2AUSP2ALDH1A1MEN1 | |
| SCHEMBL19986693 | 0.82 | ALDH1A1 (0.53) | KMT2AUSP2ALDH1A1MEN1 | |
| SCHEMBL19986461 | 0.80 | ALDH1A1 (0.52) | KMT2AUSP2ALDH1A1MEN1 | |
| SCHEMBL19986554 | 0.80 | MEN1 (0.47) | NAMPTKMT2AKCNJ6KCNJ5KCNJ3 | |
| SCHEMBL19986646 | 0.78 | ALDH1A1 (0.49) | KMT2AUSP2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050110-A1 | NOVEL CAPSID PROTEIN ASSEMBLY INHIBITOR | 正大天晴药业集团股份有限公司 | 2018-03-22 | — | — | WO | disclosed |