Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ6 | P48051 | 5/20 | 0.39 |
| ▸ | KCNJ5 | P48544 | 5/20 | 0.39 |
| ▸ | KCNJ3 | P48549 | 5/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | LYN | P07948 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19986713 | 1.00 | KCNJ6 (0.39) | KCNJ6KCNJ5KCNJ3KDRBLM | |
| SCHEMBL19986462 | 0.86 | BLM (0.42) | KCNJ6KCNJ5KCNJ3KDRBLM | |
| SCHEMBL19986607 | 0.86 | NAMPT (0.41) | KCNJ6KCNJ5KCNJ3KDRBLM | |
| SCHEMBL19986694 | 0.86 | NAMPT (0.41) | KCNJ6KCNJ5KCNJ3KDRBLM | |
| SCHEMBL19986711 | 0.82 | ALDH1A1 (0.48) | USP2KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL19986667 | 0.82 | ALDH1A1 (0.48) | USP2KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL19986517 | 0.80 | KMT2A (0.48) | KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL19986634 | 0.79 | KMT2A (0.41) | KCNJ6KCNJ5KCNJ3KDRBLM | |
| SCHEMBL19986603 | 0.78 | NAMPT (0.42) | KCNJ6KCNJ5KCNJ3KDRBLM | |
| SCHEMBL19986554 | 0.76 | MEN1 (0.47) | KCNJ6KCNJ5KCNJ3KDRBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050110-A1 | NOVEL CAPSID PROTEIN ASSEMBLY INHIBITOR | 正大天晴药业集团股份有限公司 | 2018-03-22 | — | — | WO | disclosed |