Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL141826 | 0.90 | ACHE (0.48) | ACHEGLAKMT2AEPHX1HDAC3 | |
| Benzene SCHEMBL9001703 | 0.85 | HDAC3 (0.49) | ACHEGLAKMT2AEPHX1HDAC3 | |
| SCHEMBL16248012 | 0.85 | ACHE (0.44) | ACHEGLAKMT2AEPHX1HDAC3 | |
| SCHEMBL300406 | 0.85 | ACHE (0.47) | ACHEGLAKMT2AEPHX1HDAC3 | |
| SCHEMBL5916713 | 0.83 | EPHX1 (0.50) | ACHEGLAKMT2AEPHX1HDAC3 | |
| SCHEMBL5916968 | 0.83 | EPHX1 (0.50) | ACHEGLAKMT2AEPHX1HDAC3 | |
| SCHEMBL5916602 | 0.83 | ACHE (0.42) | ACHEGLAKMT2AEPHX1HDAC3 | |
| SCHEMBL5916507 | 0.81 | ACHE (0.43) | ACHEGLAKMT2AEPHX1HDAC3 | |
| SCHEMBL139102 | 0.80 | ACHE (0.48) | ACHEGLAKMT2AEPHX1HDAC3 | |
| SCHEMBL3653026 | 0.79 | KMT2A (0.50) | ACHEGLAKMT2AEPHX1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180080858-A1 | FUNCTIONALIZED SUPPORT FOR ANALYTICAL SAMPLE PREPARATION | AGILENT TECHNOLOGIES, INC. | 2018-03-22 | — | — | US | disclosed |