SCHEMBL139102

SCHEMBL139102

CCOC(=O)NCCC[Si](OCC)(OCC)OCC

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ACHE P22303 14/20 0.48
HDAC3 O15379 1/20 0.42
HDAC4 P56524 1/20 0.42
HDAC1 Q13547 1/20 0.42
HDAC7 Q8WUI4 1/20 0.42
HDAC2 Q92769 1/20 0.42
HDAC10 Q969S8 1/20 0.42
HDAC11 Q96DB2 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
HDAC9 Q9UKV0 1/20 0.42
HDAC5 Q9UQL6 1/20 0.42
NCOR2 Q9Y618 1/20 0.42
GLA P06280 1/20 0.41
KMT2A Q03164 1/20 0.41
EPHX1 P07099 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL300412 0.95 ACHE (0.47) ACHEHDAC3HDAC4HDAC1HDAC7
SCHEMBL5916614 0.93 ACHE (0.47) ACHEHDAC3HDAC4HDAC1HDAC7
SCHEMBL5916566 0.93 ACHE (0.47) ACHEHDAC3HDAC4HDAC1HDAC7
SCHEMBL16248012 0.91 ACHE (0.44) ACHEHDAC3HDAC4HDAC1HDAC7
SCHEMBL809069 0.91 ACHE (0.61) ACHE
SCHEMBL27030671 0.89 ACHE (0.46) ACHEHDAC3HDAC4HDAC1HDAC7
SCHEMBL5916903 0.89 KMT2A (0.42) ACHEHDAC3HDAC4HDAC1HDAC7
SCHEMBL5916494 0.89 ACHE (0.42) ACHEHDAC3HDAC4HDAC1HDAC7
SCHEMBL18878216 0.88 ACHE (0.44) ACHEHDAC3HDAC4HDAC1HDAC7
SCHEMBL20544859 0.88 ACHE (0.44) ACHEHDAC3HDAC4HDAC1HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 822 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3820876-B1 PREPARATION OF ISOCYANATOSILANES MOMENTIVE PERFORMANCE MAT INC (US) 2023-09-06 EP claimed
EP-4035649-B1 DENTAL ADHESIVE COMPOSITION 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-07-26 EP claimed
US-11655263-B2 Preparation of isocyanatosilanes MOMENTIVE PERFORMANCE MATERIALS INC (US) 2023-05-23 US claimed
EP-4035649-A1 DENTAL ADHESIVE COMPOSITION 3M Innovative Properties Company (US) 2022-08-03 EP claimed
US-20210277035-A1 PREPARATION OF ISOCYANATOSILANES MOMENTIVE PERFORMANCE MATERIALS INC. 2021-09-09 US claimed
EP-3820876-A1 PREPARATION OF ISOCYANATOSILANES Momentive Performance Materials Inc. (US) 2021-05-19 EP claimed
CN-112513054-A Preparation of isocyanatosilanes 莫门蒂夫性能材料股份有限公司 2021-03-16 CN claimed
EP-1937697-B1 METHOD FOR PRODUCTION OF ISOCYANATOSILANES MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-16 EP claimed
US-8545946-B2 Liquid crystal alignment solution DAXIN MATERIALS CORPORATION (TW) 2013-10-01 US claimed
WO-2013043321-A1 POLYMER COMPOSITION AND METHOD CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2013-03-28 WO claimed
US-20060276644-A1 Process for the production of isocyanatosilane and silylisocyanurate GENERAL ELECTRIC COMPANY 2006-12-07 US claimed
WO-2006113182-A2 PROCESS FOR MAKING SILYLISOCYANURATE GENERAL ELECTRIC COMPANY (US) 2006-10-26 WO claimed
US-20060235221-A1 Process for making silylisocyanurate MOMENTIVE PERFORMANCE MATERIALS INC. 2006-10-19 US claimed
US-7060849-B1 Method for production of isocyanatosilanes GENERAL ELECTRIC COMPANY (US) 2006-06-13 US claimed
EP-0668326-B1 Covalently-nucleophilic self-curing systems FRAUNHOFER GES FORSCHUNG (DE) 2004-07-28 EP claimed
US-6673954-B1 REACTING AN AMINOORGANOSILANE WITH AN ORGANOCARBONATE ESTER, BASIC CATALYST GENERAL ELECTRIC COMPANY 2004-01-06 US claimed
US-5919885-A Covalently and nucleophilically self-curing systems FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 1999-07-06 US claimed
US-5674964-A Self-curing systems FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 1997-10-07 US claimed
EP-0668326-A2 Covalently-nucleophilic self-curing systems FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 1995-08-23 EP claimed
EP-0618242-A2 Self-curing systems FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 1994-10-05 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060235221-A1 Process for making silylisocyanurate PCMT1, SRM, STOM ACHE 1265/4885HDAC3 15/4885HDAC4 191/4885
US-20060276644-A1 Process for the production of isocyanatosilane and silylisocyanurate SI, TST, PCMT1 ACHE 1637/4885HDAC3 99/4885HDAC4 658/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.