Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 2/20 | 0.34 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.33 |
| ▸ | NT5E | P21589 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16368080 | 0.94 | FAP (0.33) | FAPSTING1NT5EADORA2AADORA2B | |
| SCHEMBL19993729 | 0.90 | FAP (0.45) | FAPSTING1NT5EADORA2A | |
| SCHEMBL16368112 | 0.87 | FAP (0.35) | FAPSTING1ADORA2AADORA2B | |
| SCHEMBL17357699 | 0.85 | FAP (0.38) | FAPSTING1ADORA2AADORA2B | |
| SCHEMBL16368193 | 0.84 | FAP (0.44) | FAPSTING1NT5EADORA2A | |
| SCHEMBL16374082 | 0.84 | FAP (0.44) | FAPSTING1NT5EADORA2A | |
| SCHEMBL16368111 | 0.81 | NT5E (0.34) | NT5EADORA2AADORA2B | |
| SCHEMBL25566020 | 0.79 | FAP (0.42) | FAPSTING1NT5EADORA2A | |
| SCHEMBL16368204 | 0.79 | FAP (0.45) | FAPSTING1NT5EADORA2A | |
| SCHEMBL16368274 | 0.77 | FAP (0.47) | FAPSTING1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180079774-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | ALIOS BIOPHARMA, INC. | 2018-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180079774-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | PNP, NUDT1, NT5C3B | FAP 1177/4885STING1 698/4885NT5E 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.