Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19986472 | 0.91 | RAPGEF4 (0.30) | RAPGEF4 | |
| SCHEMBL19986537 | 0.81 | STK17A (0.34) | LMNAKDM4E | |
| SCHEMBL19986707 | 0.79 | STK17A (0.35) | LMNA | |
| SCHEMBL19986474 | 0.79 | PDE4B (0.31) | — | |
| SCHEMBL19986468 | 0.74 | MEN1 (0.44) | LMNATSHR | |
| SCHEMBL19986510 | 0.73 | LMNA (0.65) | SMN1; SMN2LMNAKDM4ETSHR | |
| SCHEMBL28588269 | 0.68 | CA1 (0.40) | SMN1; SMN2LMNA | |
| SCHEMBL19986470 | 0.67 | MAPT (0.38) | KDM4E | |
| SCHEMBL19986658 | 0.67 | HAO1 (0.35) | — | |
| SCHEMBL19986541 | 0.67 | HAO1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050110-A1 | NOVEL CAPSID PROTEIN ASSEMBLY INHIBITOR | 正大天晴药业集团股份有限公司 | 2018-03-22 | — | — | WO | disclosed |