Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.35 |
| ▸ | STK17B | O94768 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | TDP2 | O95551 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19986537 | 0.92 | STK17A (0.34) | STK17ASTK17BLMNAHTTPLA2G1B | |
| SCHEMBL19986658 | 0.88 | HAO1 (0.35) | STK17ASTK17BHTT | |
| SCHEMBL19986727 | 0.80 | HAO1 (0.37) | STK17ALMNAHTT | |
| SCHEMBL19986620 | 0.79 | SMN1; SMN2 (0.33) | LMNA | |
| SCHEMBL19986474 | 0.79 | PDE4B (0.31) | — | |
| SCHEMBL19986706 | 0.72 | HTR2A (0.44) | HTTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL19986648 | 0.72 | KMT2A (0.50) | HTTHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL19986502 | 0.71 | KMT2A (0.60) | LMNAHTTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL19986472 | 0.70 | RAPGEF4 (0.30) | — | |
| SCHEMBL19986541 | 0.67 | HAO1 (0.33) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050110-A1 | NOVEL CAPSID PROTEIN ASSEMBLY INHIBITOR | 正大天晴药业集团股份有限公司 | 2018-03-22 | — | — | WO | disclosed |