Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | F7 | P08709 | 1/20 | 0.48 |
| ▸ | CBFB | Q13951 | 8/20 | 0.47 |
| ▸ | CHEK2 | O96017 | 4/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.44 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.44 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19986744 | 0.88 | MGLL (0.57) | ACACBCHEK2MGLLHPGD | |
| SCHEMBL19970761 | 0.87 | ACACB (0.53) | ACACBF2F10F7CBFB | |
| SCHEMBL19986737 | 0.85 | ACACB (0.51) | ACACBCHEK2MGLLALDH1A1TP53 | |
| SCHEMBL19970760 | 0.80 | ENPP2 (0.52) | ACACBCBFBMGLLNPC1RAB9A | |
| SCHEMBL19970749 | 0.76 | RUNX1 (0.56) | ACACBF2F10F7CBFB | |
| SCHEMBL19970769 | 0.75 | CBFB (0.56) | ACACBF2F10F7CBFB | |
| SCHEMBL19970849 | 0.75 | RUNX1 (0.58) | ACACBF2F10F7CBFB | |
| SCHEMBL19970732 | 0.75 | ACACB (0.52) | ACACBF2F10F7CBFB | |
| SCHEMBL19970784 | 0.74 | MGLL (0.59) | ACACBCHEK2MGLLHPGD | |
| SCHEMBL19970771 | 0.74 | CBFB (0.53) | CBFBNPC1RAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3296297-A1 | BENZIMIDAZOL DERIVATIVES FOR TREATING FILOVIRUS INFECTION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-21 | — | — | EP | disclosed |