Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.51 |
| ▸ | MGLL | Q99685 | 2/20 | 0.49 |
| ▸ | FHIT | P49789 | 1/20 | 0.48 |
| ▸ | CHEK2 | O96017 | 5/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19986744 | 0.92 | MGLL (0.57) | ACACBMGLLCHEK2HPGDBCHE | |
| SCHEMBL19970809 | 0.87 | ACACB (0.52) | ACACBMGLLFHITCHEK2HTR2B | |
| SCHEMBL19986696 | 0.85 | ACACB (0.51) | ACACBMGLLCHEK2ALDH1A1HPGD | |
| SCHEMBL19970808 | 0.80 | ENPP2 (0.51) | ACACBMGLLHTR2BMAPTALDH1A1 | |
| SCHEMBL19970784 | 0.79 | MGLL (0.59) | ACACBMGLLCHEK2HPGDBCHE | |
| SCHEMBL19970865 | 0.75 | STAT3 (0.51) | ACACBCHEK2MAPTLMNAALDH1A1 | |
| SCHEMBL19970796 | 0.75 | ACACB (0.51) | ACACBMGLLFHITCHEK2LMNA | |
| SCHEMBL19970737 | 0.75 | SLC2A1 (0.57) | ACACBBCHEACHE | |
| SCHEMBL19970859 | 0.75 | NAMPT (0.52) | ACACBCHEK2BCHEACHE | |
| SCHEMBL19970764 | 0.75 | AURKA (0.47) | CHEK2POLBMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3296297-A1 | BENZIMIDAZOL DERIVATIVES FOR TREATING FILOVIRUS INFECTION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-21 | — | — | EP | disclosed |