Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.32 |
| ▸ | SELE | P16581 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | FBP1 | P09467 | 1/20 | 0.31 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19986658 | 0.92 | HAO1 (0.35) | HAO1GFERICAM1SELEALDH1A1 | |
| SCHEMBL19986541 | 0.80 | HAO1 (0.33) | HAO1GFERALDH1A1HTTL3MBTL1 | |
| SCHEMBL19986707 | 0.80 | STK17A (0.35) | HTTSTK17ALMNA | |
| SCHEMBL19986725 | 0.69 | KMT2A (0.46) | ALDH1A1HTTL3MBTL1LMNAMAPT | |
| SCHEMBL19986472 | 0.65 | RAPGEF4 (0.30) | — | |
| SCHEMBL19986641 | 0.64 | STK17A (0.37) | ALDH1A1HTTSTK17ALMNAMAPT | |
| SCHEMBL19986657 | 0.64 | CCR1 (0.43) | ALDH1A1HTTL3MBTL1LMNAMAPT | |
| SCHEMBL19986530 | 0.62 | ALOX15 (0.58) | ALDH1A1HTTLMNAMAPT | |
| SCHEMBL9828662 | 0.60 | HTT (0.46) | ALDH1A1HTTL3MBTL1LMNAMAPT | |
| SCHEMBL14562896 | 0.58 | HAO1 (0.39) | HAO1ALDH1A1HTTAKT1FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050110-A1 | NOVEL CAPSID PROTEIN ASSEMBLY INHIBITOR | 正大天晴药业集团股份有限公司 | 2018-03-22 | — | — | WO | disclosed |