Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19987417 | 0.97 | PDK2 (0.36) | PDK2PGRALDH1A1LMNAGAA | |
| SCHEMBL15183636 | 0.90 | PDK2 (0.39) | PDK2PGRESR1ESR2ALDH1A1 | |
| SCHEMBL15183634 | 0.89 | PGR (0.42) | PDK2PGRESR1ESR2ALDH1A1 | |
| SCHEMBL15183660 | 0.87 | PDK2 (0.38) | PDK2PGRESR1ESR2ALDH1A1 | |
| SCHEMBL17901851 | 0.87 | PDK2 (0.37) | PDK2PGRALDH1A1LMNAGAA | |
| SCHEMBL17901883 | 0.87 | PDK2 (0.39) | PDK2ALDH1A1LMNAGAAPAX8 | |
| SCHEMBL12325036 | 0.86 | PGR (0.40) | PDK2PGRESR1ESR2MAPT | |
| SCHEMBL10039054 | 0.86 | PDK2 (0.41) | PDK2PGRESR1ESR2ALDH1A1 | |
| SCHEMBL808059 | 0.86 | PGR (0.40) | PDK2PGRALDH1A1LMNAL3MBTL1 | |
| SCHEMBL17901892 | 0.85 | ALDH1A1 (0.33) | PDK2ALDH1A1LMNAGAAPAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2826079-B1 | ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2021-01-20 | — | — | EP | disclosed |
| EP-2907173-B1 | ELECTRONIC DEVICE | MERCK PATENT GMBH (DE) | 2018-03-21 | — | — | EP | disclosed |