Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.33 |
| ▸ | HPGD | P15428 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | STAT1 | P42224 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19987559 | 0.89 | MRGPRX4 (0.34) | KDM4EHPGDALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL19987585 | 0.85 | HPGD (0.35) | KDM4EHPGDALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL19987547 | 0.80 | HPGD (0.35) | KDM4EHPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL17600113 | 0.77 | KDM4E (0.34) | KDM4EHPGDALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL19987602 | 0.76 | CD274 (0.33) | KDM4EHPGDALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL19987563 | 0.75 | MRGPRX4 (0.44) | HPGDALDH1A1SMN1; SMN2TDP1TSHR | |
| SCHEMBL19987543 | 0.72 | MAOB (0.43) | ALDH1A1SMN1; SMN2KMT2AMEN1CD274 | |
| SCHEMBL19987560 | 0.71 | CD274 (0.35) | HPGDCD274MMP1MMP9MMP8 | |
| SCHEMBL16273662 | 0.70 | HPGD (0.36) | KDM4EHPGDALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL18433815 | 0.70 | SMN1; SMN2 (0.40) | KDM4EHPGDALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3006440-B1 | TETRAZOLINONE COMPOUND AND APPLICATION OF SAME | SUMITOMO CHEMICAL CO (JP) | 2018-03-21 | — | — | EP | disclosed |