Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 7/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19987543 | 0.88 | MAOB (0.43) | FFAR4FFAR1POLBMAPTALDH1A1 | |
| SCHEMBL22059937 | 0.85 | MRGPRX4 (0.46) | MRGPRX4TDP1FFAR4POLBMAPT | |
| SCHEMBL19987586 | 0.82 | MRGPRX4 (0.38) | MRGPRX4FFAR4FFAR1MAPTALDH1A1 | |
| SCHEMBL19987565 | 0.81 | ELANE (0.35) | TDP1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL18749267 | 0.80 | MRGPRX4 (0.44) | MRGPRX4TDP1FFAR4FFAR1POLB | |
| SCHEMBL18749625 | 0.80 | MRGPRX4 (0.44) | MRGPRX4TDP1FFAR4FFAR1POLB | |
| SCHEMBL19987600 | 0.79 | MRGPRX4 (0.44) | MRGPRX4FFAR4MAPTALDH1A1NPC1 | |
| SCHEMBL19987564 | 0.79 | MRGPRX4 (0.35) | MRGPRX4TDP1FFAR4MAPTALDH1A1 | |
| SCHEMBL18749413 | 0.79 | MRGPRX4 (0.45) | MRGPRX4TDP1FFAR4FFAR1POLB | |
| SCHEMBL18749337 | 0.78 | MRGPRX4 (0.43) | MRGPRX4TDP1FFAR4FFAR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3006440-B1 | TETRAZOLINONE COMPOUND AND APPLICATION OF SAME | SUMITOMO CHEMICAL CO (JP) | 2018-03-21 | — | — | EP | disclosed |