Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | HPGD | P15428 | 5/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | STAT1 | P42224 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19987537 | 0.89 | KDM4E (0.33) | MRGPRX4KDM4EALDH1A1HPGDMAPK1 | |
| SCHEMBL19987585 | 0.87 | HPGD (0.35) | MRGPRX4S1PR1S1PR5KDM4EALDH1A1 | |
| SCHEMBL19987547 | 0.81 | HPGD (0.35) | MRGPRX4KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL18831293 | 0.77 | SLC22A12 (0.32) | KDM4EALDH1A1MAPK1 | |
| SCHEMBL16273640 | 0.76 | MRGPRX4 (0.34) | MRGPRX4S1PR1S1PR5KDM4EALDH1A1 | |
| SCHEMBL19987563 | 0.76 | MRGPRX4 (0.44) | MRGPRX4ALDH1A1HPGDMAPK1LMNA | |
| SCHEMBL19987543 | 0.74 | MAOB (0.43) | ALDH1A1KMT2ALMNASMN1; SMN2MEN1 | |
| SCHEMBL18767159 | 0.74 | CD274 (0.37) | MRGPRX4S1PR1S1PR5KDM4EALDH1A1 | |
| SCHEMBL19987586 | 0.73 | MRGPRX4 (0.38) | MRGPRX4KDM4EALDH1A1MAPK1KMT2A | |
| SCHEMBL19987560 | 0.72 | CD274 (0.35) | MRGPRX4S1PR1S1PR5HPGDMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3006440-B1 | TETRAZOLINONE COMPOUND AND APPLICATION OF SAME | SUMITOMO CHEMICAL CO (JP) | 2018-03-21 | — | — | EP | disclosed |